基因名:
ESRRA
产品别名:
ERR1; ERRa; ERRalpha; ESRL1; NR3B1; ESRRA; estrogen related receptor alpha; estrogen related receptor alpha; steroid hormone receptor ERR1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1; 雌激素受体相关受体α(ERRa); 雌激素受体相关蛋白α;
背景信息:
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.