基因名:
ETF1
产品别名:
D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1; ETF1; eukaryotic translation termination factor 1; eukaryotic translation termination factor 1; eukaryotic peptide chain release factor subunit 1; polypeptide chain release factor 1; protein Cl1; sup45 (yeast omnipotent suppressor 45) homolog-like 1; 真核翻译终止因子1(ETF1); 真核肽链释放因子1;
背景信息:
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X. [provided by RefSeq, Jan 2012].