基因名:
ETS1
产品别名:
ETS-1; EWSR2; c-ets-1; p54; ETS1; ETS proto-oncogene 1, transcription factor; ETS proto-oncogene 1, transcription factor; protein C-ets-1; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; V-Ets骨髓成红细胞增多症病毒E26癌基因同源物1(ETS1); 磷酸化Ets转录因子家族ets1; 转录因子家族ETS1;
背景信息:
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].