基因名：
F2
产品别名：
PT； RPRGL2； THPH1； F2； coagulation factor II, thrombin； coagulation factor II, thrombin； prothrombin； prepro-coagulation factor II； prothrombin B-chain； thrombin factor II； 凝血因子Ⅱ(F2)； 凝血因子Ⅱ(F2)天然蛋白； 凝血酶(凝血因子II)激活肽1； 凝血酶(凝血因子II)激活肽2； 凝血酶(凝血因子II)轻链； 凝血酶(凝血因子II)重链； 凝血酶原；
背景信息：
Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K.
