基因名：
FANCD2
产品别名：
FA-D2； FA4； FACD； FAD； FAD2； FANCD； FANCD2； FA complementation group D2； FA complementation group D2； Fanconi anemia group D2 protein； Fanconi anemia complementation group D2； D2组范可尼贫血偶联因子(FANCD2)； 磷酸化FANCD2；
背景信息：
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
