基因名：
FCGR3B
产品别名：
CD16； CD16-I； CD16A； CD16b； FCG3； FCGR3； FCGR3A； FCR-10； FCRIII； FCRIIIb； FCGR3B； Fc gamma receptor IIIb； Fc gamma receptor IIIb； low affinity immunoglobulin gamma Fc region receptor III-B； Fc fragment of IgG receptor IIIb； Fc fragment of IgG, low affinity IIIb, receptor (CD16b)； Fc gamma receptor III-B； Fc-gamma receptor IIIb (CD 16)； FcgammaRIIIb； fc-gamma RIII-beta； fc-gamma RIIIb； igG Fc receptor III-1； IgG-Fc片段低亲和力受体Ⅲb(FcgR3B)； IgG-Fc片段低亲和力受体Ⅲb(FcgR3B)真核蛋白；
背景信息：
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
