基因名:
FDXR
产品别名:
ADR; ADXR; ANOA; FDXR; ferredoxin reductase; ferredoxin reductase; NADPH:adrenodoxin oxidoreductase, mitochondrial; AR; adrenodoxin reductase; adrenodoxin-NADP(+) reductase; epididymis secretory sperm binding protein; ferredoxin--NADP(+) reductase; 铁氧化还原蛋白还原酶; 铁氧还蛋白还原酶(FDXR);
背景信息:
Adrenodoxin Reductase (ADX Reductase) is a mitochondrial flavoprotein that receives electrons from NADPH and thereby initiates the electron-transport chain serving mitochondrial cytochromes P450. ADX Reductase participates in cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-? hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney and sterol C-27 hydroxylation in the liver. Alternate splicing of ADX Reductase produces two isoforms. Human ADX Reductase maps to human chromosome 17q24-q25.