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重组成纤维细胞生长因子8蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组成纤维细胞生长因子8(FGF8)蛋白
Recombinant FGF8
基因名:

FGF8


产品别名:

AIGF; FGF-8; HBGF-8; HH6; KAL6; FGF8; fibroblast growth factor 8; fibroblast growth factor 8; fibroblast growth factor 8; androgen-induced growth factor; fibroblast growth factor 8 (androgen-induced); heparin-binding growth factor 8; 成纤维细胞生长因子8; 成纤维细胞生长因子8(FGF8);


背景信息:
This protein is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
 
 
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