基因名:
FKBP4
产品别名:
FKBP51; FKBP52; FKBP59; HBI; Hsp56; PPIase; p52; FKBP4; FKBP prolyl isomerase 4; FKBP prolyl isomerase 4; peptidyl-prolyl cis-trans isomerase FKBP4; FK506 binding protein 4, 59kDa; HSP binding immunophilin; T-cell FK506-binding protein, 59kD; peptidylprolyl cis-trans isomerase; rotamase; FK506结合蛋白4(FKBP4); 热休克蛋白56;
背景信息:
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.