基因名:
FOXO3
产品别名:
AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A; FOXO3; forkhead box O3; forkhead box O3; forkhead box protein O3; FOXO3A-; forkhead box O3A; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; 叉头框蛋白O3(FOXO3); 叉头蛋白O3A; 磷酸化叉头蛋白3A;
背景信息:
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]