基因名:
MLANA
产品别名:
MART-1; MART1; MLANA; melan-A; melan-A; melanoma antigen recognized by T-cells 1; antigen LB39-AA; antigen SK29-AA; epididymis secretory sperm binding protein; protein Melan-A; 黑色素瘤相关抗原/黑色素-A;
背景信息:
Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.