基因名：
NR5A2
产品别名：
B1F； B1F2； CPF； FTF； FTZ-F1； FTZ-F1beta； LRH-1； LRH1； hB1F-2； NR5A2； nuclear receptor subfamily 5 group A member 2； nuclear receptor subfamily 5 group A member 2； nuclear receptor subfamily 5 group A member 2； CYP7A promoter-binding factor； b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus； fetoprotein-alpha 1 (AFP) transcription factor； hepatocytic transcription factor hB1F-3； 成纤维细胞核受体Nr5a2； 肝受体同源物1(LRH1)；
背景信息：
NR5A2 is a pre-adipocyte-specific nuclear receptor that regulates expression of aromatase in adipose tissue. NR5A2 belongs to the fushi tarazu factor-1 subfamily of orphan nuclear receptors. NR5A2 transcripts are abundant in the human ovary and testis and are predominantly expressed in tissues of endodermal origin. NR5A2 is a positive transcription factor for ABCG5 and ABCG8 and regulates genes involved in sterol and bile acid secretion from liver and intestine. It induces cell proliferation through the concomitant induction of cyclin D1 and E1, an effect that is potentiated by its interaction with beta-catenin.
