基因名：
FUT4
产品别名：
CD15； ELFT； FCT3A； FUC-TIV； FUTIV； LeX； SSEA-1； FUT4； fucosyltransferase 4； fucosyltransferase 4； alpha-(1,3)-fucosyltransferase 4； 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase； ELAM ligand fucosyltransferase； ELAM-1 ligand fucosyltransferase； Lewis X； alpha (1,3) fucosyltransferase, myeloid-specific； fucT-IV； fucosyltransferase IV； galactoside 3-L-fucosyltransferase； stage-specific embryonic antigen 1； CD15分子(CD15)； α-(1,3)-岩藻糖基转移酶 4；
背景信息：
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq].
