基因名：
GABRA4
产品别名：
GABRA4； gamma-aminobutyric acid type A receptor subunit alpha4； gamma-aminobutyric acid type A receptor subunit alpha4； gamma-aminobutyric acid receptor subunit alpha-4； GABA(A) receptor, alpha 4； gamma-aminobutyric acid (GABA) A receptor, alpha 4； gamma-aminobutyric acid A receptor alpha 4； gamma-aminobutyric acid type A receptor alpha4 subunit； G氨基丁酸A型受体α4/GABAA Rα4； γ-氨基丁酸A受体α4(gABRa4)；
背景信息：
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
