基因名：
GAD2
产品别名：
GAD65； GAD2； glutamate decarboxylase 2； glutamate decarboxylase 2； glutamate decarboxylase 2； 65 kDa glutamic acid decarboxylase； GAD-65； Glutamate decarboxylase-2 (pancreas)； glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)； 谷氨酸脱羧酶-65； 谷氨酸脱羧酶2(GAD2)； 谷氨酸脱羧酶65+谷氨酸脱羧酶67；
背景信息：
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
