基因名：
GCHFR
产品别名：
GFRP； HsT16933； P35； GCHFR； GTP cyclohydrolase I feedback regulator； GTP cyclohydrolase I feedback regulator； GTP cyclohydrolase 1 feedback regulatory protein； GTP cyclohydrolase I feedback regulatory protein； GTP环反馈调节蛋白；
背景信息：
GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15.
