基因名:
GCKR
产品别名:
FGQTL5; GKRP; GCKR; glucokinase regulator; glucokinase regulator; glucokinase regulatory protein; glucokinase (hexokinase 4) regulator; hexokinase 4 regulator; 葡萄糖激酶调节蛋白; 葡萄糖激酶调节蛋白(GKRP);
背景信息:
GCKR is a subfamily member of the SIS (Sugar ISomerase) family of proteins. It is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young.