基因名:
GDF1
产品别名:
CERS1; CHTD6; DORV; DTGA3; LAG1; LASS1; RAI; UOG1; GDF1; growth differentiation factor 1; growth differentiation factor 1; embryonic growth/differentiation factor 1; Ceramide synthase 1; LAG1 longevity assurance homolog 1; Longevity assurance gene 1 protein homolog 1; Protein UOG-1; 生长分化因子1; 生长分化因子1(GDF1);
背景信息:
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene.