基因名：
GNAQ
产品别名：
CMC1； G-ALPHA-q； GAQ； SWS； GNAQ； G protein subunit alpha q； G protein subunit alpha q； guanine nucleotide-binding protein G(q) subunit alpha； epididymis secretory sperm binding protein； guanine nucleotide binding protein (G protein), q polypeptide； guanine nucleotide-binding protein alpha-q； G蛋白α亚单位蛋白Q；
背景信息：
GNAQ belong to the family of heterotrimeric Guanine nucleotide-binding proteins proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. GNAQ is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. in recent studies over expression of GNAQ is associated with cardiomyocyte apoptosis.
