基因名:
GNGT1
产品别名:
GNG1; HG3G1; GNGT1; G protein subunit gamma transducin 1; G protein subunit gamma transducin 1; guanine nucleotide-binding protein G(T) subunit gamma-T1; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; heterotrimeric guanine nucleotide-binding protein 3G1; transducin gamma chain; G蛋白γ1/Gγ1;
背景信息:
Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].