基因名:
UTS2R
产品别名:
GPR14; UR-2-R; UTR; UTR2; UTS2R; urotensin 2 receptor; urotensin 2 receptor; urotensin-2 receptor; G-protein coupled receptor 14; UR-II-R; urotensin II receptor; G蛋白偶联受体14; 尾加压素2受体(UTS2R);
背景信息:
GPCR GPR14 has been reported to be expressed at high levels in the heart and pancreas and also in artery and smooth muscle. Low transcript levels have been identified in brain, particularly in thalamus, superior occipital gyrus, and substantia nigra.
GPR14 is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. Referenced from Swiss-Prot Q9UKP6.