基因名:
GRIK1
产品别名:
EAA3; EEA3; GLR5; GLUR5; GluK1; gluR-5; GRIK1; glutamate ionotropic receptor kainate type subunit 1; glutamate ionotropic receptor kainate type subunit 1; glutamate receptor ionotropic, kainate 1; GluK1(del_e2); excitatory amino acid receptor 3; glutamate receptor 5; 谷氨酸受体红藻氨酸离子1;
背景信息:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]