基因名：
GRIK5
产品别名：
EAA2； GRIK2； GluK5； KA2； GRIK5； glutamate ionotropic receptor kainate type subunit 5； glutamate ionotropic receptor kainate type subunit 5； glutamate receptor ionotropic, kainate 5； excitatory amino acid receptor 2； glutamate receptor KA2； putative NMDtranscript(altDon_e2)； putative NMDtranscript(del_e13-e15)； 谷氨酸受体红藻氨酸离子5；
背景信息：
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of the structurally related subunits GluR-1 to -7, KA1 and KA2. KA1 (also designated EEA1) and KA2 (also designated EEA2) form heteromeric receptors with GluR subunits when coexpressed, forming ion channels with various properties. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate.
