基因名:
GRIN1
产品别名:
DEE101; GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1; GRIN1; glutamate ionotropic receptor NMDA type subunit 1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor ionotropic, NMDA 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; putative NMDtranscript(altAcc_e2); N-甲基-D-天氡氨酸离子能谷氨酸受体1(GRIN1); 磷酸化离子型谷氨酸受体1; 磷酸化谷氨酸受体1; 离子型谷氨酸受体1; 谷氨酸受体1; 谷氨酸受体NMDAζ1;
背景信息:
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]