基因名:
GRIN2A
产品别名:
EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A; GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor ionotropic, NMDA 2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; glutamate ionotropic receptor NMDA 2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; N-甲基-D-天氡氨酸离子能谷氨酸受体2A(GRIN2A); 磷酸化谷氨酸受体1; 磷酸化谷氨酸受体2A; 磷酸化谷氨酸受体2A+2B; 谷氨酸受体2A;
背景信息:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]