基因名：
GRIN2D
产品别名：
DEE46； EB11； EIEE46； GluN2D； NMDAR2D； NR2D； GRIN2D； glutamate ionotropic receptor NMDA type subunit 2D； glutamate ionotropic receptor NMDA type subunit 2D； glutamate receptor ionotropic, NMDA 2D； N-methyl D-aspartate receptor subtype 2D； N-methyl-d-aspartate receptor subunit 2D； estrogen receptor binding CpG island； glutamate [NMDA] receptor subunit epsilon-4； glutamate receptor, ionotropic, N-methyl D-aspartate 2D； N-甲基-D-天氡氨酸离子能谷氨酸受体2D(GRIN2D)； 谷氨酸受体2D；
背景信息：
NR2D is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NR2D is expressed in the brain; it is detected in embryonic stages, peaks at postnatal day 7, and decreases thereafter to adult levels.
[FUNCTION] NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. [SUBUNIT] Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Interacts with PDZ domains of INADL and DLG4. [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Expressed in brain, mainly in the subcortical region. [SIMILARITY] Belongs to the glutamate-gated ion channel.
