基因名：
CXCL1
产品别名：
FSP； GRO1； GROa； MGSA； MGSA-a； NAP-3； SCYB1； CXCL1； C-X-C motif chemokine ligand 1； C-X-C motif chemokine ligand 1； growth-regulated alpha protein； C-X-C motif chemokine 1； GRO-alpha(1-73)； GRO1 oncogene (melanoma growth stimulating activity, alpha)； GRO1 oncogene (melanoma growth-stimulating activity)； MGSA alpha； chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)； fibroblast secretory protein； melanoma growth stimulating activity, alpha； melanoma growth stimulatory activity alpha； neutrophil-activating protein 3； 趋化因子(C-X-C基序)配体1(CXCL1)； 趋化因子(C-X-C基序)配体1(CXCL1)真核蛋白； 黑色素瘤生长刺激活性蛋白α/GROa；
背景信息：
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.
