基因名：
GSTA1
产品别名：
GST-epsilon； GST2； GSTA1-1； GTH1； GSTA1； glutathione S-transferase alpha 1； glutathione S-transferase alpha 1； glutathione S-transferase A1； 13-hydroperoxyoctadecadienoate peroxidase； GST HA subunit 1； GST class-alpha member 1； S-(hydroxyalkyl)glutathione lyase A1； androst-5-ene-3,17-dione isomerase； glutathione S-alkyltransferase A1； glutathione S-aryltransferase A1； glutathione S-transferase 2； glutathione S-transferase Ha subunit 1； testicular tissue protein Li 80； 谷胱甘肽S转移酶α1； 谷胱甘肽S转移酶α1(GSTa1)；
背景信息：
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy.
