基因名:
GSTM2
产品别名:
GST4; GSTM; GSTM2-2; GTHMUS; GSTM2; glutathione S-transferase mu 2; glutathione S-transferase mu 2; glutathione S-transferase Mu 2; GST class-mu 2; GST, muscle; S-(hydroxyalkyl)glutathione lyase M2; epididymis secretory sperm binding protein; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; glutathione S-aryltransferase M2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-transferase M2 (muscle); glutathione S-transferase mu 2 (muscle); 谷胱甘肽S转移酶M2; 谷胱甘肽S转移酶μ2(GSTM2);
背景信息:
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta. Butyrate, an important luminal component produced from the fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotective by increasing detoxification capabilities in the colon mucosa.