基因名:
GSTT1
产品别名:
GSTT1; glutathione S-transferase theta 1; glutathione S-transferase theta 1; glutathione S-transferase theta-1; GST class-theta-1; glutathione transferase T1-1; 谷胱甘肽S转移酶θ/Glutathione S Transferase theta 1; 谷胱甘肽S转移酶θ1(GSTt1);
背景信息:
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq, Jul 2008].