基因名:
GZMA
产品别名:
CTLA3; HFSP; GZMA; granzyme A; granzyme A; granzyme A; CTL tryptase; Cytotoxic T-lymphocyte-associated serine esterase-3; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); HF; Hanukah factor serine protease); cytotoxic T-lymphocyte proteinase 1; fragmentin-1; granzyme 1; granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); h factor; 颗粒酶A; 颗粒酶A(GZMA); 颗粒酶A(GZMA)真核蛋白;
背景信息:
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]