基因名:
H1-4
产品别名:
H1.4; H1E; H1F4; H1s-4; HIST1H1E; RMNS; dJ221C16.5; H1-4; H1.4 linker histone, cluster member; H1.4 linker histone, cluster member; histone H1.4; H1 histone family, member 4; histone 1, H1e; histone H1b; histone H1s-4; histone cluster 1 H1 family member e; histone cluster 1, H1e; 乙酰化组蛋白H1b; 磷酸化三甲基化组蛋白H1; 磷酸化组蛋白H1,4样蛋白; 磷酸化组蛋白H1.4; 组蛋白H1.4样蛋白;
背景信息:
Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.