基因名：
HBG2
产品别名：
HBG-T1； TNCY； HBG2； hemoglobin subunit gamma 2； hemoglobin subunit gamma 2； hemoglobin subunit gamma-2； G-gamma globin Paulinia； abnormal hemoglobin； gamma globin； gamma-2-globin； gamma-globin chain； hb F Ggamma； hemoglobin gamma-2 chain； hemoglobin gamma-G chain； hemoglobin, gamma G； methemoglobin； 血红蛋白γ2； 血红蛋白γ2(HBg2)；
背景信息：
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
