基因名：
HDGF
产品别名：
HMG1L2； HDGF； heparin binding growth factor； heparin binding growth factor； hepatoma-derived growth factor； epididymis secretory sperm binding protein； hepatoma derived growth factor； high mobility group protein 1-like 2； 肝癌源性生长因子(HDGF)； 肝癌衍生生长因子/高迁移率族蛋白1样蛋白2；
背景信息：
Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.
