基因名：
HMGB2
产品别名：
HMG2； HMGB2； high mobility group box 2； high mobility group box 2； high mobility group protein B2； HMG-2； high mobility group protein 2； high-mobility group (nonhistone chromosomal) protein 2； 高迁移率族框蛋白2(HMGB2)； 高迁移率族蛋白2；
背景信息：
High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
