基因名:
HMGB3
产品别名:
HMG-2a; HMG-4; HMG2A; HMG4; HMGB3; high mobility group box 3; high mobility group box 3; high mobility group protein B3; high mobility group protein 2a; high-mobility group (nonhistone chromosomal) protein 4; 高迁移率家族蛋白3; 高迁移率族框蛋白3(HMGB3);
背景信息:
High Mobility Group Protein B3 (HMGB3) belongs to the HMGB family. Members of the HMG box subfamily are thought to be have an important role in DNA replication, nucleosome assembly and transcription. HMGB3 binds preferentiallly single-stranded DNA and unwinds double stranded DNA. HMGB3 consists of 200 amino acids and is localized to the cell nucleus. It contains two HMG box DNA-binding domain. HMGB3 binds preferentially single-stranded DNA and unwinds double stranded DNA.