KIRA6 (KIRA-6) is a novel, potent and ATP-competitive allosteric IRE1α inhibitor (IC50 of 0.6 μM) with anti-inflammatory and immune-modulating properties. KIRA6 has been developed to inhibit IRE1α-mediated cell death, and has
been demonstrated to promote cell survival and prevent ER stress-induced
cell degeneration in vivo
纯度:≥98%
CAS:1589527-65-0