基因名:
FOXA2
产品别名:
HNF-3-beta; HNF3B; TCF3B; FOXA2; forkhead box A2; forkhead box A2; hepatocyte nuclear factor 3-beta; forkhead box protein A2; hepatic nuclear factor-3-beta; transcription factor 3B; 叉头框蛋白A2(FOXA2); 肝细胞核因子3;
背景信息:
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]