基因名:
HNRNPK
产品别名:
AUKS; CSBP; HNRPK; TUNP; HNRNPK; heterogeneous nuclear ribonucleoprotein K; heterogeneous nuclear ribonucleoprotein K; heterogeneous nuclear ribonucleoprotein K; dC-stretch binding protein; transformation upregulated nuclear protein; 不均一核核糖核蛋白K(HNRPK); 异质核糖核蛋白K; 磷酸化异质核糖核蛋白K;
背景信息:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq].