基因名:
HPN
产品别名:
TMPRSS1; HPN; hepsin; hepsin; serine protease hepsin; testicular tissue protein Li 85; transmembrane protease serine 1; 跨膜蛋白酶丝氨酸1;
背景信息:
This gene encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non-catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants.