基因名：
HSD11B1
产品别名：
11-DH； 11-beta-HSD1； CORTRD2； HDL； HSD11； HSD11B； HSD11L； SDR26C1； HSD11B1； hydroxysteroid 11-beta dehydrogenase 1； hydroxysteroid 11-beta dehydrogenase 1； 11-beta-hydroxysteroid dehydrogenase 1； 7-oxosteroid reductase； corticosteroid 11-beta-dehydrogenase isozyme 1； short chain dehydrogenase/reductase family 26C member 1； 11-β-羟基类固醇脱氢酶1(HSD11b1)； 羟基类固醇脱氢酶11β1；
背景信息：
HSD11B1 is a microsomal enzyme that catalyses the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyse the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
