重组NDST1蛋白

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重组NDST1蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant NDST1
Recombinant N-deacetylase and N-sulfotransferase 1 protein

基因名：

NDST1

产品别名：

HSST； MRT46； NST1； NDST1； N-deacetylase and N-sulfotransferase 1； N-deacetylase and N-sulfotransferase 1； bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1； HSNST 1； N-Deacetylase-N-sulfotransferase 1； N-HSST 1； N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1； N-deacetylase/N-sulfotransferase 1； N-heparan sulfate sulfotransferase 1； NDST-1； [Heparan sulfate]-glucosamine N-sulfotransferase 1； glucosaminyl N-deacetylase/N-sulfotransferase 1； heparan sulfate-N-deacetylase/N-sulfotransferase； heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1； NDST1蛋白；

背景信息：

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.