基因名：
IFNGR1
产品别名：
CD119； IFNGR； IMD27A； IMD27B； IFNGR1； interferon gamma receptor 1； interferon gamma receptor 1； interferon gamma receptor 1； AVP, type 2； CD119 antigen； CDw119； IFN-gamma receptor 1； IFN-gamma-R-alpha； IFN-gamma-R1； antiviral protein, type 2； immune interferon receptor 1； interferon-gamma receptor alpha chain； 干扰素-gamma受体1； 干扰素γ受体1(IFNgR1)； 磷酸化干扰素gamma受体1蛋白；
背景信息：
Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
