基因名:
IFNGR2
产品别名:
AF-1; IFGR2; IFNGT1; IMD28; IFNGR2; interferon gamma receptor 2; interferon gamma receptor 2; interferon gamma receptor 2; IFN-gamma receptor 2; IFN-gamma-R-beta; IFN-gamma-R2; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; interferon gamma transducer 1; 干扰素-gamma受体2/干扰素-gamma受体β/IFN-γRβ;
背景信息:
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2.