基因名：
IGFBP2
产品别名：
IBP2； IGF-BP53； IGFBP2； insulin like growth factor binding protein 2； insulin like growth factor binding protein 2； insulin-like growth factor-binding protein 2； IGF-binding protein 2； insulin-like growth factor binding protein 2, 36kDa； 胰岛素样生长因子结合蛋白2； 胰岛素样生长因子结合蛋白2(IGFBP2)； 胰岛素样生长因子结合蛋白2(IGFBP2)真核蛋白；
背景信息：
IGFBP-2, also known as IGFBP2, is a insulin-like growth factor-binding protein (IGFBP). IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to a potential involvement of IGFBP2 in tumorigenesis.
