基因名：
IGFBP3
产品别名：
BP-53； IBP3； IGFBP3； insulin like growth factor binding protein 3； insulin like growth factor binding protein 3； insulin-like growth factor-binding protein 3； IBP-3； IGF-binding protein 3； IGFBP-3； acid stable subunit of the 140 K IGF complex； binding protein 29； binding protein 53； growth hormone-dependent binding protein； 胰岛素样生长因子结合蛋白3； 胰岛素样生长因子结合蛋白3(IGFBP3)； 胰岛素样生长因子结合蛋白3(IGFBP3)真核蛋白；
背景信息：
This protein is a member of the insulin-like growth factor binding protein (IGFBP) with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
