基因名：
IGHG3
产品别名：
IgG3； IGHG3； immunoglobulin heavy constant gamma 3 (G3m marker)； immunoglobulin heavy constant gamma 3 (G3m marker)； C gamma 3； constant region of heavy chain of IgG3； immunoglobulin gamma 3 (Gm marker)； immunoglobulin heavy constant gamma 3 (Gm marker)； secrete-type Ig gamma heavy-chain； 免疫球蛋白G3(IgG3)； 免疫球蛋白G3(IgG3)天然蛋白；
背景信息：
IGHG3 (Immunoglobulin Heavy Constant Gamma 3 (G3m Marker), also known as IgG3) is a Protein Coding gene. Ig gamma-3 chain C region is a protein that in humans is encoded by the IGHG3 gene. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Murine immunoglobulin G (IgG) plays an important role in mediating protective immune responses to malaria. Diseases associated with IGHG3 include Heavy Chain Disease and Gamma Heavy Chain Disease. Among its related pathways are IL4-mediated signaling events and the Creation of C4 and C2 activators.
