基因名:
INPP5B
产品别名:
5PTase; INPP5B; inositol polyphosphate-5-phosphatase B; inositol polyphosphate-5-phosphatase B; type II inositol 1,4,5-trisphosphate 5-phosphatase; inositol polyphosphate-5-phosphatase, 75kDa; phosphoinositide 5-phosphatase; 聚磷酸肌醇磷酸酶5B;
背景信息:
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]