重组SH2结构含磷酸肌醇SHIP1蛋白

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重组SH2结构含磷酸肌醇SHIP1蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组磷酸化SH2结构含磷酸肌醇SHIP1蛋白
Recombinant INPP5D

基因名：

INPP5D

产品别名：

SHIP； SHIP-1； SHIP1； SIP-145； hp51CN； p150Ship； INPP5D； inositol polyphosphate-5-phosphatase D； inositol polyphosphate-5-phosphatase D； phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1； SH2 domain-containing inositol 5'-phosphatase 1； inositol polyphosphate-5-phosphatase, 145kD； inositol polyphosphate-5-phosphatase, 145kDa； phosphatidylinositol 4,5-bisphosphate 5-phosphatase； signaling inositol polyphosphate 5 phosphatase SIP-145； signaling inositol polyphosphate phosphatase SHIP II； SH2结构含磷酸肌醇SHIP1；磷酸化SH2结构含磷酸肌醇SHIP1；

背景信息：

SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。