基因名：
ITGA2B
产品别名：
BDPLT16； BDPLT2； CD41； CD41B； GP2B； GPIIb； GT； GT1； GTA； HPA3； PPP1R93； ITGA2B； integrin subunit alpha 2b； integrin subunit alpha 2b； integrin alpha-IIb； GPalpha IIb； alphaIIb protein； integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)； platelet fibrinogen receptor, alpha subunit； platelet glycoprotein IIb of IIb/IIIa complex； platelet membrane glycoprotein IIb； platelet-specific antigen BAK； protein phosphatase 1, regulatory subunit 93； 整合素α2B(ITGa2B)； 血小板膜糖蛋白Ⅱb；
背景信息：
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
